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Glutaredoxin 1 Protein (GRX1) (AA 1-106) (His tag)

GRX1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181166
  • Target Alle Glutaredoxin 1 (GRX1) Proteine anzeigen
    Glutaredoxin 1 (GRX1)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-106
    Spezies
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 14
    • 5
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Glutaredoxin 1 Protein ist gelabelt mit His tag.
    Sequenz
    AA 1-106
    Produktmerkmale
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 12.7 kDa under reducing (R) condition (SDS-PAGE).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product GRX1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 150 mM NaCl, pH 7.5 with 1 mM DTT
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Barinova, Serebryakova, Muronetz, Schmalhausen: "S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase induces formation of C150-C154 intrasubunit disulfide bond in the active site of the enzyme." in: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 12, pp. 3167-3177, (2018) (PubMed).

  • Target
    Glutaredoxin 1 (GRX1)
    Andere Bezeichnung
    Glutaredoxin 1 (GRX1 Produkte)
    Synonyme
    Glrx1 Protein, Grx Protein, grx Protein, wu:fc38f02 Protein, zgc:103707 Protein, GLRXL Protein, Grx1 Protein, TTase Protein, C86710 Protein, D13Wsu156e Protein, grx1 Protein, GLRX Protein, GRX Protein, GRX1 Protein, GLRX1 Protein, TTF Protein, glrx Protein, glutaredoxin Protein, glutaredoxin (thioltransferase) Protein, glutaredoxin Grx1 Protein, NrdH-redoxin Protein, Uncharacterized monothiol glutaredoxin F10D7.3 Protein, glutaredoxin-1 (Grx1) Protein, temporal expression: late Protein, glutaredoxin L homeolog Protein, Glrx Protein, glrx Protein, GLRX Protein, grx1 Protein, AF_RS07750 Protein, F10D7.3 Protein, AFUA_1G06100 Protein, NT01EI_2528 Protein, O2L Protein, glrx.L Protein
    Substanzklasse
    Viral Protein
    Hintergrund
    Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.
    Molekulargewicht
    12.7 kDa
    NCBI Accession
    NP_001112362
    Pathways
    Cell RedoxHomeostasis
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