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CD22 Molecule (CD22) (AA 176-687) (Active) protein (His tag) Protein

CD22 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2180726
$319.00
Zzgl. Versandkosten $45.00
Lieferung in 21 bis 31 Werktagen
  • Target Alle CD22 Proteine anzeigen
    CD22
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 176-687
    Spezies
    • 18
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD22 Protein ist gelabelt mit His tag.
    Sequenz
    AA 176-687
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 57.8 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    CD22
    Andere Bezeichnung
    Siglec-2 (CD22 Produkte)
    Synonyme
    A530093D23, Lyb-8, Lyb8, SIGLEC-2, SIGLEC2, siglec-2, CD22 antigen, CD22 molecule, Cd22, CD22
    Hintergrund
    B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
    Molekulargewicht
    58.1 kDa
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