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NEU1 Protein (AA 48-415) (His tag)

NEU1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN2115431
  • Target Alle NEU1 Proteine anzeigen
    NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 48-415
    Spezies
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses NEU1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Sialidase-1/NEU-1 (C-6His)
    Sequenz
    ENDFGLVQPL VTMEQLLWVS GRQIGSVDTF RIPLITATPR GTLLAFAEAR KMSSSDEGAK FIALRRSMDQ GSTWSPTAFI VNDGDVPDGL NLGAVVSDVE TGVVFLFYSL CAHKAGCQVA STMLVWSKDD GVSWSTPRNL SLDIGTEVFA PGPGSGIQKQ REPRKGRLIV CGHGTLERDG VFCLLSDDHG ASWRYGSGVS GIPYGQPKQE NDFNPDECQP YELPDGSVVI NARNQNNYHC HCRIVLRSYD ACDTLRPRDV TFDPELVDPV VAAGAVVTSS GIVFFSNPAH PEFRVNLTLR WSFSNGTSWR KETVQLWPGP SGYSSLATLE GSMDGEEQAP QLYVLYEKGR NHYTESISVA KISVYGTLVD HHHHHH
    Produktmerkmale
    Recombinant Human Sialidase-1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu48-Leu415) of Human NEU1 fused with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
    Andere Bezeichnung
    Sialidase-1 (NEU1 Produkte)
    Synonyme
    NANH Protein, NEU Protein, SIAL1 Protein, MGC81958 Protein, AA407268 Protein, AA407316 Protein, Aglp Protein, Apl Protein, Bat-7 Protein, Bat7 Protein, G9 Protein, Map-2 Protein, Neu Protein, Neu-1 Protein, neuraminidase 1 Protein, neuraminidase 1 (lysosomal sialidase) L homeolog Protein, NEU1 Protein, neu1.L Protein, neu1 Protein, Neu1 Protein
    Hintergrund
    Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues, it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.
    Synonyms: Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal Sialidase, N-Acetyl-Alpha-Neuraminidase 1, NEU1, NANH
    Molekulargewicht
    41.27 kDa
    UniProt
    Q99519
    Pathways
    SARS-CoV-2 Protein Interaktom
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