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VEGFD Protein (AA 93-201) (His tag)

Figf Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN2115424
  • Target Alle VEGFD (Figf) Proteine anzeigen
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 93-201
    Spezies
    • 9
    • 3
    • 3
    • 2
    Human
    Quelle
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses VEGFD Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human VEGF-D/FIGF (C-6His)
    Sequenz
    FYDIETLKVI DEEWQRTQCS PRETCVEVAS ELGKSTNTFF KPPCVNVFRC GGCCNEESLI CMNTSTSYIS KQLFEISVPL TSVPELVPVK VANHTGCKCL PTAPRHPYSH HHHHH
    Produktmerkmale
    Recombinant Human Vascular Endothelial Growth Factor D/VEGFD produced by our mammalian expression system in human cells is expressed with sequence (Phe93-Ser201) of Human VEGFD.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product Figf Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    Andere Bezeichnung
    VEGFD-FIGF (Figf Produkte)
    Synonyme
    FIGF Protein, vegfd Protein, vegf-d Protein, VEGFD Protein, AI325264 Protein, VEGF-D Protein, Vegfd Protein, Vegf-d Protein, vascular endothelial growth factor D Protein, Vascular endothelial growth factor D Protein, VEGFD Protein, vegfd Protein, vegfd.L Protein, Vegfd Protein
    Hintergrund
    Vascular endothelial growth factor D (VEGF-D), also known as c-fos-induced growth factor (FIGF), is a secreted glycoprotein of the VEGF/PDGF family. VEGFs regulate angiogenesis and lymphangiogenesis during development and tumor growth, and are characterized by eight conserved cysteine residues that form a cystine knot structure.Mouse and human VEGF-D are ligands for VEGF Receptor 3 (VEGF R3, also called Flt4) that are active across species and show enhanced affinity when processed . Processed human VEGF-D is also a ligand for VEGF R2, also called Flk1 or KDR. VEGF R3 is strongly expressed in lymphatic endothelial cells and is essential for regulation of the growth and differentiation of lymphatic endothelium. While VEGF-C is the critical ligand for VEGF R3 during embryonic lymphatic development, VEGF-D is most active in neonatal lymphatic maturation and bone growth. Both promote tumor lymphangiogenesis. Consonant with their activity on VEGF receptors, binding of VEGF-C and VEGF-D.
    Synonyms: Vascular Endothelial Growth Factor D, VEGF-D, c-Fos-Induced Growth Factor, FIGF, VEGFD
    Molekulargewicht
    12.18 kDa
    UniProt
    O43915
    Pathways
    RTK Signalweg
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