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NOV Protein (AA 32-357)

NOV Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018277
  • Target Alle NOV Proteine anzeigen
    NOV (Nephroblastoma Overexpressed (NOV))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 32-357
    Spezies
    • 6
    • 5
    • 2
    • 1
    • 1
    Human
    Quelle
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    CHO Cells
    Produktmerkmale
    ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product NOV Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Human NOV remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human NOV should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    NOV (Nephroblastoma Overexpressed (NOV))
    Andere Bezeichnung
    Nephroblastoma Overexpressed Gene Protein (NOV) (NOV Produkte)
    Synonyme
    CCN3 Protein, IBP-9 Protein, IGFBP-9 Protein, IGFBP9 Protein, NOVh Protein, nov-A Protein, xnov Protein, NovH Protein, C130088N23Rik Protein, nephroblastoma overexpressed Protein, nephroblastoma overexpressed L homeolog Protein, nephroblastoma overexpressed gene Protein, NOV Protein, nov.L Protein, Nov Protein
    Hintergrund
    Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
    Synonyms: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
    Molekulargewicht
    20-50 kDa, observed by reducing SDS-PAGE.
    UniProt
    P48745
    Pathways
    Smooth Muscle Cell Migration, Growth Factor Binding
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