Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-92) protein (Fc Tag)

Details zu Produkt Nr. ABIN2007463, Anbieter: Anmelden zum Anzeigen
  • I-309
  • P500
  • SCYA1
  • SISe
  • TCA3
  • BF534335
  • Scya1
  • Tca-3
  • CCLi6
  • chemokine
  • C-C motif chemokine ligand 1
  • chemokine (C-C motif) ligand 1
  • CCL1
  • Ccl1
AA 24-92
Human Cells
Aufreinigungstag / Konjugat
Dieses CCL1 Protein ist gelabelt mit Fc Tag.
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Hersteller Produkt- Nr.
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Produktmerkmale The recombinant mouse CCL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 330 amino acids and has a calculated molecular mass of 36.2 kDa. As a result of glycosylation, the apparent molecular mass of the monomer is approximately 44 kDa in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the secreted form of mouse CCL1 isoform 1 (P10146-1) (Lys 24-Cys 92) was fused with the Fc region of human IgG1 at the N-terminus.
Predicted N-Term: Glu
Reinheit > 92 % as determined by SDS-PAGE
Endotoxin-Niveau < 1.0 EU per μg of the protein as determined by the LAL method
Hintergrund Synonyms: BF534335,I-309,Scya1,Tca-3
Molekulargewicht 36.2 kDa, 44 kDa
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Buffer Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handhabung Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Lagerung -20 °C,-80 °C
Informationen zur Lagerung Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-92) protein (Fc Tag) (ABIN2007463) Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-92) protein (Fc Tag)
Allgemeine Veröffentlichungen Spinetti, Bernardini, Camarda, Mangoni, Santoni, Capogrossi, Napolitano: "The chemokine receptor CCR8 mediates rescue from dexamethasone-induced apoptosis via an ERK-dependent pathway." in: Journal of leukocyte biology, Vol. 73, Issue 1, pp. 201-7, 2003 (PubMed).

Bernardini, Spinetti, Ribatti, Camarda, Morbidelli, Ziche, Santoni, Capogrossi, Napolitano: "I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo." in: Blood, Vol. 96, Issue 13, pp. 4039-45, 2000 (PubMed).

Horuk, Hesselgesser, Zhou, Faulds, Halks-Miller, Harvey, Taub, Samson, Parmentier, Rucker, Doranz, Doms: "The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains." in: The Journal of biological chemistry, Vol. 273, Issue 1, pp. 386-91, 1998 (PubMed).

Roos, Loetscher, Legler, Clark-Lewis, Baggiolini, Moser: "Identification of CCR8, the receptor for the human CC chemokine I-309." in: The Journal of biological chemistry, Vol. 272, Issue 28, pp. 17251-4, 1997 (PubMed).

Miller, Krangel: "The human cytokine I-309 is a monocyte chemoattractant." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 7, pp. 2950-4, 1992 (PubMed).

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