Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415), (full length) (Active) protein (GST tag)

Details zu Produkt Nr. ABIN2003170, Anbieter: Anmelden zum Anzeigen
Proteinname
  • HsT1201
  • PAI
  • PAI-2
  • PAI2
  • PLANH2
  • SERPINB2
  • Planh2
  • ovalbumin
  • Pai2a
  • serpin family B member 2
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2
  • serine (or cysteine) peptidase inhibitor, clade B, member 2
  • SERPINB2
  • Serpinb2
Proteineigenschaft
full length, AA 1-415
5
4
3
2
1
1
1
1
1
1
Spezies
Human
15
5
4
Quelle
Baculovirus infected Insect Cells
14
2
2
2
1
1
Protein-Typ
Recombinant
Biologische Aktivität
Active
Aufreinigungstag / Konjugat
Dieses SERPINB2 Protein ist gelabelt mit GST tag.
Applikation
Functional Studies (Func), SDS-PAGE (SDS)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktmerkmale The recombinant human SERPINB2/GST chimera consists of 640 amino acids and predicts a molecular mass of 73 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the full length of human SERPINB2 (NP_002566.1) (Met 1-Pro 415) was fused with the GST tag at the N-terminus.
Predicted N-Term: Met
Reinheit > 95 % as determined by SDS-PAGE
Endotoxin-Niveau < 1.0 EU per μg of the protein as determined by the LAL method
Biological Activity Comment Immobilized human GST-SerpinB2 at 10 μg/ml (100 μl/well) can bind biotinylated human uPA-His , The EC50 of biotinylated human uPA-His is 10.24-23.88 ng/ml.
Hintergrund Synonyms: HsT1201,PAI,PAI-2,PAI2,PLANH2
Molekulargewicht 73 kDa, 65 kDa
NCBI Accession NP_002566
Pathways Autophagie
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Buffer Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 0.5 mM Reduced Glutathione, 10 % glycerol, 0.5 mM PMSF
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handhabung Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Lagerung -20 °C,-80 °C
Informationen zur Lagerung Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415), (full length) (Active) protein (GST tag) (ABIN2003170) Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415), (full length) (Active) protein (GST tag)
Allgemeine Veröffentlichungen Gillard, Scarff, Loveland, Ricardo, Bird: "Modulation and redistribution of proteinase inhibitor 8 (Serpinb8) during kidney regeneration." in: American journal of nephrology, Vol. 26, Issue 1, pp. 34-42, 2006

Gillard, Scarff, Loveland, Ricardo, Bird: "Modulation and redistribution of proteinase inhibitor 8 (Serpinb8) during kidney regeneration." in: American journal of nephrology, Vol. 26, Issue 1, pp. 34-42, 2006 (PubMed).

Rawlings, Tolle, Barrett: "Evolutionary families of peptidase inhibitors." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 705-16, 2004 (PubMed).

Sumi, Ichikawa, Nakamura, Miura, Aoki: "Expression and characterization of pro alpha 2-plasmin inhibitor." in: Journal of biochemistry, Vol. 106, Issue 4, pp. 703-7, 1990 (PubMed).

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