Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) protein (His tag)

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Proteinname
  • HC14
  • MCP-2
  • MCP2
  • SCYA10
  • SCYA8
  • 1810063B20Rik
  • AB023418
  • Mcp2
  • Scya8
  • C-C motif chemokine ligand 8
  • chemokine (C-C motif) ligand 8
  • C-C motif chemokine 8
  • monocyte chemoattractant protein-2 precursor
  • CCL8
  • Ccl8
  • LOC101119572
  • MCP-2
Proteineigenschaft
AA 24-99
13
2
2
2
1
1
1
1
Spezies
Human
31
21
2
1
1
1
1
Quelle
Human Cells
45
3
3
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
His tag
Applikation
Functional Studies (Func)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Verwendungszweck Recombinant Human C-C Motif Chemokine 8/CCL8/MCP-2 (C-6His)
Sequenz QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTQRGKE VCADPKERWV RDSMKHLDQI FQNLKPVDHH HHHH
Produktmerkmale Recombinant Human C-C Motif Chemokine 8/CCL8 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln24-Pro99) of Human CCL8 fused with a polyhistidine tag at the C-terminus.
Reinheit > 95 % as determined by reducing SDS-PAGE.
Sterilität 0.2 μm filtered
Endotoxin-Niveau Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Proteinname
Sub Type Fusionprotein
Hintergrund Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.
Alternative Names: C-C Motif Chemokine 8, HC14, Monocyte Chemoattractant Protein 2, Monocyte Chemotactic Protein 2, MCP-2, Small-Inducible Cytokine A8, CCL8, MCP2, SCYA10, SCYA8
Molekulargewicht 9.95 kDa
UniProt P80075
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,1 mM EDTA, pH 7.4.
Handhabung Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Lagerung 4 °C/-20 °C/-80 °C
Informationen zur Lagerung Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Haltbarkeit 3 months
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