IL10RB Protein (AA 20-220) (Fc Tag)

Produktnummer ABIN1880651

Produktdetails

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-220

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses IL10RB Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human IL-10 Receptor Subunit β/IL-10RB (C-Fc)

Sequenz: MVPPPENVRM NSVNFKNILQ WESPAFAKGN LTFTAQYLSY RIFQDKCMNT TLTECDFSSL SKYGDHTLRV RAEFADEHSD WVNITFCPVD DTIIGPPGMQ VEVLADSLHM RFLAPKIENE YETWTMKNVY NSWTYNVQYW KNGTDEKFQI TPQYDFEVLR NLEPWTTYCV QVRGFLPDRN KAGEWSEPVC EQTTHDETVP SVDDIEGRMD EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK

Produktmerkmale: Recombinant Human Interleukin-10 receptor subunit beta/ IL-10RB is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met20-Ser220) of Human IL10RB fused with a FC tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Andere Bezeichnung: Interleukin-10 Receptor Subunit beta/ IL-10RB (IL10RB Produkte)

Synonyme: IL10R2 Protein, IL10RB Protein, il10r2 Protein, CDW210B Protein, CRF2-4 Protein, CRFB4 Protein, D21S58 Protein, D21S66 Protein, IL-10R2 Protein, 6620401D04Rik Protein, AI528744 Protein, Crfb4 Protein, D16H21S58 Protein, D21S58h Protein, Il10r2 Protein, RGD1560373 Protein, interleukin 10 receptor subunit beta Protein, interleukin 10 receptor subunit beta S homeolog Protein, interleukin-10 receptor subunit beta Protein, interleukin 10 receptor, beta Protein, IL10RB Protein, il10rb.S Protein, LOC473966 Protein, LOC478404 Protein, il10rb Protein, Il10rb Protein

Hintergrund: Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

Molekulargewicht: 50.6 kDa

UniProt: Q08334