SEMA4B Protein (AA 39-712) (Fc Tag,His tag)

Produktnummer ABIN1880643

Produktdetails

Target: SEMA4B (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4B (SEMA4B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 39-712

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SEMA4B Protein ist gelabelt mit Fc Tag,His tag.

Verwendungszweck: Recombinant Human Semaphorin-4B/SEMA4B (C-Fc-6His)

Sequenz: LSPRISLPLG SEERPFLRFE AEHISNYTAL LLSRDGRTLY VGAREALFAL SSNLSFLPGG EYQELLWGAD AEKKQQCSFK GKDPQRDCQN YIKILLPLSG SHLFTCGTAA FSPMCTYINM ENFTLARDEK GNVLLEDGKG RCPFDPNFKS TALVVDGELY TGTVSSFQGN DPAISRSQSL RPTKTESSLN WLQDPAFVAS AYIPESLGSL QGDDDKIYFF FSETGQEFEF FENTIVSRIA RICKGDEGGE RVLQQRWTSF LKAQLLCSRP DDGFPFNVLQ DVFTLSPSPQ DWRDTLFYGV FTSQWHRGTT EGSAVCVFTM KDVQRVFSGL YKEVNRETQQ WYTVTHPVPT PRPGACITNS ARERKINSSL QLPDRVLNFL KDHFLMDGQV RSRMLLLQPQ ARYQRVAVHR VPGLHHTYDV LFLGTGDGRL HKAVSVGPRV HIIEELQIFS SGQPVQNLLL DTHRGLLYAA SHSGVVQVPM ANCSLYRSCG DCLLARDPYC AWSGSSCKHV SLYQPQLATR PWIQDIEGAS AKDLCSASSV VSPSFVPTGE KPCEQVQFQP NTVNTLACPL LSNLATRLWL RNGAPVNASA SCHVLPTGDL LLVGTQQLGE FQCWSLEEGF QQLVASYCPE VVEDGVADQT DEGGSVPVII STSRVSAPAG GKASWGADRS YWKEVDDIEG RMDEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

Produktmerkmale: Recombinant Human Semaphorin-4B/SEMA4B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu39-Glu712) of Human SEMA4B fused with a polyhistidine tag and FC tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: SEMA4B (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4B (SEMA4B))

Andere Bezeichnung: Semaphorin-4B/SEMA4B (SEMA4B Produkte)

Hintergrund: Semaphorin-4B, also known as KIAA1745, SEMAC and SEMA4B, is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.

Molekulargewicht: 102 kDa

UniProt: Q9NPR2