IFNA4 Protein (AA 24-189) (His tag)

Produktnummer ABIN1880639

Produktdetails

Target: IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 24-189

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses IFNA4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Interferon α-4/IFNA4 (C-6His)

Sequenz: CDLPQTHSLG NRRALILLAQ MGRISHFSCL KDRHDFGFPE EEFDGHQFQK TQAISVLHEM IQQTFNLFST EDSSAAWEQS LLEKFSTELY QQLNDLEACV IQEVGVEETP LMNEDSILAV RKYFQRITLY LTEKKYSPCA WEVVRAEIMR SLSFSTNLQK RLRRKDVDHH HHHH

Produktmerkmale: Recombinant Human Interferon alpha-4/IFNA4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Cys24-Asp189) of Human IFNA4 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))

Andere Bezeichnung: Interferon alpha-4/IFNA4 (IFNa4 Produkte)

Synonyme: IFN-alpha4a Protein, INFA4 Protein, Ifa4 Protein, interferon alpha 4 Protein, interferon, alpha 4 Protein, interferon-alpha-4 Protein, IFNA4 Protein, Ifna4 Protein, LOC100052921 Protein

Sub Type: Fusionprotein

Hintergrund: Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
Alternative Names: Interferon alpha-4(IFNA4), also known as Interferon alpha-4B, Interferon alpha-76 and Interferon alpha-M1, belongs to the alpha/beta interferon family.

Molekulargewicht: 20.4 kDa

UniProt: P05014

Pathways: JAK-STAT Signalweg, Hepatitis C