CD320 Protein (AA 36-231) (His tag)

Produktnummer ABIN1880633

Produktdetails

Target: CD320 (CD320 Molecule (CD320))

Protein-Typ: Recombinant

Proteineigenschaft: AA 36-231

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CD320 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 (C-6His)

Sequenz: SPLSTPTSAQ AAGPSSGSCP PTKFQCRTSG LCVPLTWRCD RDLDCSDGSD EEECRIEPCT QKGQCPPPPG LPCPCTGVSD CSGGTDKKLR NCSRLACLAG ELRCTLSDDC IPLTWRCDGH PDCPDSSDEL GCGTNEILPE GDATTMGPPV TLESVTSLRN ATTMGPPVTL ESVPSVGNAT SSSAGDQSGS PTAYGVVDHH HHHH

Produktmerkmale: Recombinant Human CD320/TCblR/8D6A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser36-Val231) of Human CD320 fused with a FC tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 10 mM Tris-Citrate,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD320 (CD320 Molecule (CD320))

Andere Bezeichnung: CD320 (CD320 Produkte)

Synonyme: 8D6 Protein, 8D6A Protein, TCBLR Protein, 425O18-1 Protein, D17Ertd716e Protein, NG29 Protein, VLDL Protein, RGD1305860 Protein, TCblR Protein, CD320 molecule Protein, CD320 antigen Protein, CD320 Protein, Cd320 Protein

Hintergrund: CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.

Molekulargewicht: 21.1 kDa

UniProt: Q9NPF0