UPRT Protein (AA 1-309) (His tag)

Produktnummer ABIN1692485

Produktdetails

Target: UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-309

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UPRT Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Uracil Phosphoribosyltransferase Homolog/UPRT (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MATELQCPDS MPCHNQQVNS ASTPSPEQLR PGDLILDHAG GNRASRAKVI LLTGYAHSSL PAELDSGACG GSSLNSEGNS GSGDSSSYDA PAGNSFLEDC ELSRQIGAQL KLLPMNDQIR ELQTIIRDKT ASRGDFMFSA DRLIRLVVEE GLNQLPYKEC MVTTPTGYKY EGVKFEKGNC GVSIMRSGEA MEQGLRDCCR SIRIGKILIQ SDEETQRAKV YYAKFPPDIY RRKVLLMYPI LSTGNTVIEA VKVLIEHGVQ PSVIILLSLF STPHGAKSII QEFPEITILT TEVHPVAPTH FGQKYFGTD

Produktmerkmale: Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp309) of Human UPRT fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))

Andere Bezeichnung: UPRT (UPRT Produkte)

Synonyme: Gm774 Protein, FUR1 Protein, UPP Protein, uracil phosphoribosyltransferase Protein, uracil phosphoribosyltransferase homolog Protein, Uprt Protein, UPRT Protein

Sub Type: Fusionprotein

Hintergrund: UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
Alternative Names: Uracil phosphoribosyltransferase homolog, UPP, FUR1, UPRT

Molekulargewicht: 35.9 kDa

UniProt: Q96BW1

Pathways: Ribonucleoside Biosynthetic Process