CGRP Protein (AA 58-141) (His tag)

Produktnummer ABIN1692417

Produktdetails

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 58-141

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CGRP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Calcitonin/CALCA (C-6His, E. coli)

Sequenz: YVQMKASELE QEQEREGSSL DSPRSKRCGN LSTCMLGTYT QDFNKFHTFP QTAIGVGAPG KKRDMSSDLE RDHRPHVSMP QNANVEHHHH HH

Produktmerkmale: Recombinant Human Calcitonin/CALCA is produced with our E. coli expression system. The target protein is expressed with sequence (Tyr58-Asn141) of Human CALCA fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,50 % Glycerol, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Andere Bezeichnung: CALCA (CALCA Produkte)

Synonyme: CALC1 Protein, CGRP Protein, CGRP-I Protein, CGRP1 Protein, CT Protein, KC Protein, CALC Protein, CALCA Protein, CALC3 Protein, ci-ct Protein, calca Protein, CA Protein, CGRP-1 Protein, Calc Protein, Calc1 Protein, Cgrp Protein, Ct Protein, Ctn Protein, calcitonin Protein, CAL6 Protein, Cal1 Protein, RATCAL6 Protein, CGRPI Protein, calc Protein, cgrp Protein, zgc:92886 Protein, calcitonin related polypeptide alpha Protein, calcitonin related polypeptide beta Protein, calcitonin-related polypeptide alpha Protein, calcitonin Protein, calcitonin/calcitonin-related polypeptide, alpha Protein, calcitonin-related polypeptide beta Protein, calcitonin gene-related peptide 2 Protein, CALCA Protein, CALCB Protein, ci-ct Protein, calca Protein, Calca Protein, LOC100008771 Protein

Sub Type: Fusionprotein

Hintergrund: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Alternative Names: Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1

Molekulargewicht: 10.5 kDa

UniProt: P01258

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour