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BNIP3 Protein (BCL2/adenovirus E1B 19kDa Interacting Protein 3) (AA 1-166) (His tag)

BNIP3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1692197
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  • Target Alle BNIP3 Proteine anzeigen
    BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-166
    Spezies
    • 2
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses BNIP3 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human BNIP3/NIP3 (N-6His)
    Sequenz
    MNHKVHHHHH HMSQNGAPGM QEESLQGSWV ELHFSNNGNG GSVPASVSIY NGDMEKILLD AQHESGRSSS KSSHCDSPPR SQTPQDTNRA SETDTHSIGE KNSSQSEEDD IERRKEVESI LKKNSDWIWD WSSRPENIPP KEFLFKHPKR TATLSMRNTS VMKKGGIFSA EFLKVFLLSR PAV
    Produktmerkmale
    Recombinant Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3/BNIP3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu166) of Human BNIP3 fused with a His tag at the N-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
    Andere Bezeichnung
    BNIP3 (BNIP3 Produkte)
    Synonyme
    NIP3, Nip3, BCL2 interacting protein 3, BCL2/adenovirus E1B interacting protein 3, BNIP3, Bnip3
    Sub Type
    Fusionprotein
    Hintergrund
    BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process.
    Alternative Names: BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3, BNIP3, NIP3
    Molekulargewicht
    20.6 kDa
    UniProt
    Q12983
    Pathways
    Autophagie, Brown Fat Cell Differentiation
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