TRIM Protein (AA 29-186) (His tag)

Produktnummer ABIN1691981

Produktdetails

Target: TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 29-186

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TRIM Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human T Cell Receptor Interacting Molecule/TRIM/TCRIM/TRAT1 (C-6His)

Sequenz: MNISHYVEKQ RQDKMYSYSS DHTRVDEYYI EDTPIYGNLD DMISEPMDEN CYEQMKARPE KSVNKMQEAT PSAQATNETQ MCYASLDHSV KGKRRKPRKQ NTHFSDKDGD EQLHAIDASV SKTTLVDSFS PESQAVEENI HDDPIRLFGL IRAKREPINL EHHHHHH

Produktmerkmale: Recombinant Human T-Cell Receptor-Associated Transmembrane Adapter 1/TRAT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Asn29-Asn186) of Human TRAT1 fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,10 % Glycerol, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))

Andere Bezeichnung: TRAT1 (TRAT1 Produkte)

Synonyme: TCRIM Protein, TRIM Protein, C030046M14Rik Protein, Tcrim Protein, Trim Protein, T cell receptor associated transmembrane adaptor 1 Protein, T-cell receptor associated transmembrane adaptor 1 Protein, TRAT1 Protein, Trat1 Protein

Sub Type: Fusionprotein

Hintergrund: T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Alternative Names: T-Cell Receptor-Associated Transmembrane Adapter 1, T-Cell Receptor-Interacting Molecule, TRIM, pp29/30, TRAT1, TCRIM, HSPC062

Molekulargewicht: 19.4 kDa

UniProt: Q6PIZ9

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung