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EPH Receptor B1 Protein (EPHB1) (AA 18-540) (Fc Tag)

EPHB1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691526
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  • Target Alle EPH Receptor B1 (EPHB1) Proteine anzeigen
    EPH Receptor B1 (EPHB1)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 18-540
    Spezies
    • 10
    • 5
    • 2
    Human
    Quelle
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses EPH Receptor B1 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human Ephrin B Receptor 1/EphB1 (C-Fc)
    Sequenz
    MEETLMDTRT ATAELGWTAN PASGWEEVSG YDENLNTIRT YQVCNVFEPN QNNWLLTTFI NRRGAHRIYT EMRFTVRDCS SLPNVPGSCK ETFNLYYYET DSVIATKKSA FWSEAPYLKV DTIAADESFS QVDFGGRLMK VNTEVRSFGP LTRNGFYLAF QDYGACMSLL SVRVFFKKCP SIVQNFAVFP ETMTGAESTS LVIARGTCIP NAEEVDVPIK LYCNGDGEWM VPIGRCTCKP GYEPENSVAC KACPAGTFKA SQEAEGCSHC PSNSRSPAEA SPICTCRTGY YRADFDPPEV ACTSVPSGPR NVISIVNETS IILEWHPPRE TGGRDDVTYN IICKKCRADR RSCSRCDDNV EFVPRQLGLT ECRVSISSLW AHTPYTFDIQ AINGVSSKSP FPPQHVSVNI TTNQAAPSTV PIMHQVSATM RSITLSWPQP EQPNGIILDY EIRYYEKEHN EFNSSMARSQ TNTARIDGLR PGMVYVVQVR ARTVAGYGKF SGKMCFQTLT DDDYKSELRE QLPVDDIEGR MDEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGK
    Produktmerkmale

    Recombinant Human Ephrin B Receptor 1/EphB1 (C-Fc)

    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    EPH Receptor B1 (EPHB1)
    Andere Bezeichnung
    Ephrin Type-B Receptor 1/EphB1 (EPHB1 Produkte)
    Synonyme
    ELK, EPHT2, Hek6, NET, ephb1-a, xek, Xek, MGC89790, EPHB1, CEK6, EK6, 9330129L11, AW488255, C130099E04Rik, Cek6, ENSMUSG00000074119, Elk, Elkh, Net, Ephb2, Erk, elk, EPH receptor B1, EPH receptor B1 S homeolog, ephrin type-B receptor 1, Eph receptor B1, EPHB1, ephb1.S, ephb1, LOC100467687, Ephb1
    Hintergrund
    Recombinant Human Ephrin Type-B Receptor 1/EphB1 is produced by our mammalian expression system. The target protein is expressed with sequence (Met18-Pro540) of Human EPHB1 fused with a FC tag at the C-terminus.
    Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases involved in the development of embryonic nervous and vascular systems. EPHB1 contains two fibronectin type-III domains, one protein kinase domain and one Sterile α Motif (SAM)domain. EPHB1 is able to stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which is also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to Ephrin-B1, Ephrin-B2 and Ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
    Molekulargewicht
    85.5 kDa
    UniProt
    P54762
    Pathways
    RTK Signalweg
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