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CD99 Protein (CD99) (AA 23-122) (Fc Tag)

CD99 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691518
$313.50
Zzgl. Versandkosten $45.00
Lieferung in 4 Werktagen
  • Target Alle CD99 Proteine anzeigen
    CD99
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 23-122
    Spezies
    • 17
    • 4
    • 3
    • 1
    Human
    Quelle
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD99 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human CD99/MIC2 (C-Fc)
    Sequenz
    DGGFDLSDAL PDNENKKPTA IPKKPSAGDD FDLGDAVVDG ENDDPRPPNP PKPMPNPNPN HPSSSGSFSD ADLADGVSGG EGKGGSDGGG SHRKEGEEAD VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
    Produktmerkmale

    Recombinant Human CD99/MIC2 (C-Fc)

    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD99
    Andere Bezeichnung
    CD99 (CD99 Produkte)
    Synonyme
    1110061M03Rik, 2410026K10Rik, D4, Pilr-l, pilr-1, HBA71, MIC2, MIC2X, MIC2Y, MSK5X, CD99 antigen, CD99 molecule (Xg blood group), CD99 molecule, Cd99, CD99
    Substanzklasse
    Viral Protein
    Hintergrund
    Recombinant Human CD99/MIC2/MIC2X/MIC2Y is produced by our mammalian expression system. The target protein is expressed with sequence (Asp23-Asp122) of Human CD99 fused with a FC tag at the C-terminus.
    CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 AAs. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48 % aa sequence identity to mouse CD99.
    Molekulargewicht
    37.2 kDa
    UniProt
    P14209
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