OB Cadherin Protein (AA 23-617) (His tag)

Produktnummer ABIN1691424

Produktdetails

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-617

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses OB Cadherin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cadherin-11/OB-Cadherin/CDH11 (C-6His)

Sequenz: FAPERRGHLR PSFHGHHEKG KEGQVLQRSK RGWVWNQFFV IEEYTGPDPV LVGRLHSDID SGDGNIKYIL SGEGAGTIFV IDDKSGNIHA TKTLDREERA QYTLMAQAVD RDTNRPLEPP SEFIVKVQDI NDNPPEFLHE TYHANVPERS NVGTSVIQVT ASDADDPTYG NSAKLVYSIL EGQPYFSVEA QTGIIRTALP NMDREAKEEY HVVIQAKDMG GHMGGLSGTT KVMITLTDVN DNPPKFPQSV YQMSVSEAAV PGEEVGRVKA KDPDIGENGL VTYNIVDGDG MESFEITTDY ETQEGVIKLK KPVDFETKRA YSLKVEAANV HIDPKFISNG PFKDTVTVKI AVEDADEPPM FLAPSYIHEV QENAAAGTVV GRVHAKDPDA ANSPIRYSID RHTDLDRFFT INPEDGFIKT TKPLDREETA WLNITVFAAE IHNRHQEAKV PVAIRVLDVN DNAPKFAAPY EGFICESDQT KPLSNQPIVT ISADDKDDTA NGPRFIFSLP PEIIHNPNFT VRDNRDNTAG VYARRGGFSR QKQDLYLLPI VISDGGIPPM SSTNTLTIKV CGCDVNGALL SCNAEAYILN AGLSTVDHHH HHH

Produktmerkmale:

Recombinant Human Cadherin-11/OB-Cadherin/CDH11 (C-6His)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Andere Bezeichnung: CDH11 (CDH11 Produkte)

Synonyme: cad11 Protein, cdhob Protein, osf-4 Protein, Xcad-11 Protein, MGC108014 Protein, OB-cadherin Protein, cadherin-11 Protein, Cad11 Protein, cdhvn Protein, vnc Protein, CAD11 Protein, CDHOB Protein, OB Protein, OSF-4 Protein, cadherin 11 Protein, cadherin 11, type 2, OB-cadherin (osteoblast) Protein, cadherin 11 S homeolog Protein, CDH11 Protein, cdh11 Protein, Cdh11 Protein, cdh11.S Protein

Hintergrund: Recombinant Human Cadherin 11 Type 2 OB-Cadherin (Osteoblast)/CDH11 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe23-Thr617) of Human CDH11 fused with a polyhistidine tag at the C-terminus.
Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

Molekulargewicht: 66.63 kDa

UniProt: Q96CZ9