AHSA1 Protein (His tag)

Produktnummer ABIN1686742

Produktdetails

Target: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Protein-Typ: Recombinant

Spezies: Saccharomyces cerevisiae

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses AHSA1 Protein ist gelabelt mit His tag.

Applikation: Western Blotting (WB), SDS-PAGE (SDS), Functional Studies (Func)

Sequenz: MGHHHHHHMV VNNPNNWHWV DKNCIGWAKE YFKQKLVGVE AGSVKDKKYA KIKSVSSIEG DCEVNQRKGK VISLFDLKIT VLIEGHVDSK DGSALPFEGS INVPEVAFDS EASSYQFDIS IFKETSELSE AKPLIRSELL PKLRQIFQQF GKDLLATHGN DIQVPESQVK SNYTRGNQKS SFTEIKDSAS KPKKNALPSS TSTSAPVSST NKVPQNGSGN STSIYLEPTF NVPSSELYET FLDKQRILAW TRSAQFFNSG PKLETKEKFE LFGGNVISEL VSCEKDKKLV FHWKLKDWSA PFNSTIEMTF HESQEFHETK LQVKWTGIPV GEEDRVRANF EEYYVRSIKL TFGFGAVL

Spezifität: ~405 kDa

Aufreinigung: Affinity Purified

Reinheit: >90%

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

This product has been certified >90% pure using SDS - PAGE analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: 12.5 mM Hepes buffer pH 7.2, 10 mM NaCl, 50 % glycerol

Lagerung: -20 °C

Antigendetails

Target: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Andere Bezeichnung: Aha1 (AHSA1 Produkte)

Synonyme: ahsa1 Protein, MGC52884 Protein, MGC132147 Protein, MGC80312 Protein, AHSA1 Protein, MGC89589 Protein, wu:fb83b05 Protein, zgc:136821 Protein, zgc:56075 Protein, AHA1 Protein, C14orf3 Protein, p38 Protein, BC023857 Protein, AHA1, activator of heat shock 90kDa protein ATPase homolog 1 S homeolog Protein, activator of Hsp90 ATPase activity 1 Protein, AHA1, activator of heat shock 90kDa protein ATPase homolog 1 L homeolog Protein, activator of HSP90 ATPase activity 1 Protein, AHA1, activator of heat shock 90kDa protein ATPase homolog 1 Protein, AHA1, activator of heat shock protein ATPase homolog 1a Protein, AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) Protein, AHA1, activator of heat shock protein ATPase 1 Protein, ahsa1.S Protein, AHSA1 Protein, ahsa1.L Protein, ahsa1 Protein, ahsa1a Protein, Ahsa1 Protein

Hintergrund: Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).

Molekulargewicht: Approx. 40.5 kDa

Gen-ID: 851800

NCBI Accession: NM_001180522

UniProt: Q12449