GPX3 Protein (AA 21-226) (DYKDDDDK Tag)

Produktnummer ABIN1344361

Produktdetails

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-226

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GPX3 Protein ist gelabelt mit DYKDDDDK Tag.

Applikation: SDS-PAGE (SDS)

Kreuzreaktivität: Human

Produktmerkmale: Human GPX3 (aa 21-226) is fused at the N-terminus to a FLAG®-tag.

Reinheit: >90 % (SDS-PAGE)

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.2.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Haltbarkeit: 3 months

Antigendetails

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Andere Bezeichnung: GPX3 (GPX3 Produkte)

Synonyme: GPX3 Protein, DKFZp469D1932 Protein, AA960521 Protein, EGPx Protein, GPx Protein, GSHPx-3 Protein, GSHPx-P Protein, GPx-3 Protein, GPx-P Protein, Gpxp Protein, glutathione peroxidase 3 Protein, gpx3 Protein, GPX3 Protein, Gpx3 Protein

Hintergrund: Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.

Molekulargewicht: ~30kDa (SDS-PAGE)

UniProt: P22352

Pathways: Thyroid Hormone Synthesis