DLL4 Protein (AA 1-532, Extracellular Domain) (Fc Tag)
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- Target Alle DLL4 Proteine anzeigen
- DLL4 (delta-Like 4 (DLL4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- Extracellular Domain, AA 1-532
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses DLL4 Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Maus
- Produktmerkmale
- Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >90 % (SDS-PAGE)
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product DLL4 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Inhibits adipogenesis of 3T3L-1 cells.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Haltbarkeit
- 3 months
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- Target
- DLL4 (delta-Like 4 (DLL4))
- Andere Bezeichnung
- DLL4 (DLL4 Produkte)
- Synonyme
- hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
- Hintergrund
- The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
- Molekulargewicht
- ~95kDa (SDS-PAGE)
- UniProt
- Q9JI71
- Pathways
- Notch Signalweg
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