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DLL4 Protein (AA 1-532, Extracellular Domain) (Fc Tag)

DLL4 Spezies: Maus Wirt: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
Produktnummer ABIN1344207
  • Target Alle DLL4 Proteine anzeigen
    DLL4 (delta-Like 4 (DLL4))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Extracellular Domain, AA 1-532
    Spezies
    • 13
    • 4
    • 3
    Maus
    Quelle
    • 8
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses DLL4 Protein ist gelabelt mit Fc Tag.
    Applikation
    SDS-PAGE (SDS)
    Kreuzreaktivität
    Maus
    Produktmerkmale
    Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
    Reinheit
    >90 % (SDS-PAGE)
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product DLL4 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Inhibits adipogenesis of 3T3L-1 cells.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    Haltbarkeit
    3 months
  • Target
    DLL4 (delta-Like 4 (DLL4))
    Andere Bezeichnung
    DLL4 (DLL4 Produkte)
    Synonyme
    hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
    Hintergrund
    The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
    Molekulargewicht
    ~95kDa (SDS-PAGE)
    UniProt
    Q9JI71
    Pathways
    Notch Signalweg
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