Hexosaminidase A Protein (HEXA) (His tag)
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- Target Alle Hexosaminidase A (HEXA) Proteine anzeigen
- Hexosaminidase A (HEXA)
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Hexosaminidase A Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product HEXA Protein
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- Kommentare
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Synonyms: beta-hexosaminidase subunit alpha, TSD, hexosaminidase A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- Hexosaminidase A (HEXA)
- Andere Bezeichnung
- HEXA (HEXA Produkte)
- Synonyme
- TSD Protein, fc04h11 Protein, wu:fc04h11 Protein, wu:fv09f06 Protein, si:dkey-35i22.2 Protein, HEXA Protein, Hex-1 Protein, zgc:112084 Protein, hexosaminidase subunit alpha Protein, hexosaminidase B (beta polypeptide) Protein, CUGBP Elav-like family member 6 Protein, hexosaminidase A Protein, hexosaminidase A (alpha polypeptide) Protein, beta-hexosaminidase subunit alpha-like Protein, HEXA Protein, hexb Protein, CELF6 Protein, Hexa Protein, hexa Protein, LOC100228061 Protein
- Hintergrund
- HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Recombinant human HEXA protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 52.9 kDa (464aa)
- NCBI Accession
- NP_000511
- Pathways
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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