MAFK Protein (His tag)

Produktnummer ABIN1098756

Produktdetails

Target: MAFK (Transcription Factor MafK (MAFK))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MAFK Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Transcription factor MafK, NFE2U, P18

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: MAFK (Transcription Factor MafK (MAFK))

Andere Bezeichnung: MAFK (MAFK Produkte)

Synonyme: NFE2U Protein, P18 Protein, AW061068 Protein, NF-E2 Protein, Nfe2u Protein, MAF bZIP transcription factor K Protein, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) Protein, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K Protein, Mafk Protein, MAFK Protein, mafk Protein

Hintergrund: MAFK belongs to the bZIP family and Maf subfamily. Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. Small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Recombinant human MAFK protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 19.7 kDa (176aa)

NCBI Accession: NP_002351