SLAMF1 Protein (His tag)
-
- Target Alle SLAMF1 Proteine anzeigen
- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses SLAMF1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SLAMF1 Protein
-
-
- Kommentare
-
Synonyms: signaling lymphocytic activation molecule precursor, CD150, CDw150, SLAM
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
-
- Target
- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
- Andere Bezeichnung
- SLAMF1 (SLAMF1 Produkte)
- Synonyme
- CD150 Protein, SLAM Protein, SLAMF1 Protein, 4933415F16 Protein, AA177906 Protein, CDw150 Protein, ESTM51 Protein, IPO-3 Protein, Slam Protein, RGD1560634 Protein, signaling lymphocytic activation molecule family member 1 Protein, SLAMF1 Protein, Slamf1 Protein
- Hintergrund
- SLAMF1 belongs to the immunoglobulin gene superfamily and is involved in T-cell stimulation. This protein is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. High-affinity for self-ligand is important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. Recombinant human SLAMF1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 26.7kDa (240aa)
- NCBI Accession
- NP_003028
-