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RCAN3 Protein (His tag)

RCAN3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN1098701
  • Target Alle RCAN3 Proteine anzeigen
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 1
    • 1
    Human
    Quelle
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses RCAN3 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Reinheit
    > 90 % by SDS - PAGE
  • Kommentare

    Synonyms: Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
    Lagerung
    4 °C
    Informationen zur Lagerung
    Avoid repeated freezing and thawing cycles.
  • Target
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Andere Bezeichnung
    RCAN3 (RCAN3 Produkte)
    Synonyme
    DSCR1L2 Protein, rcn3 Protein, hrcn3 Protein, mcip3 Protein, dscr1l2 Protein, MGC145788 Protein, MCIP3 Protein, RCN3 Protein, hRCN3 Protein, Dscr1l2 Protein, AU041093 Protein, Csp3 Protein, wu:fc68f05 Protein, zgc:113155 Protein, zgc:91820 Protein, RCAN family member 3 Protein, calcipressin-3 Protein, regulator of calcineurin 3 Protein, RCAN3 Protein, Tsp_08182 Protein, rcan3 Protein, Rcan3 Protein
    Hintergrund
    Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molekulargewicht
    23.5 kDa (209aa)
    NCBI Accession
    NP_038469
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