MFAP2 Protein (His tag)
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- Target Alle MFAP2 Proteine anzeigen
- MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses MFAP2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MFAP2 Protein
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- Kommentare
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Synonyms: Microfibrillar-associated protein 2, Microfibrillar-associated protein 2, MAGP, MAGP-1, MAGP1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 M Urea, 20% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))
- Andere Bezeichnung
- MFAP2 (MFAP2 Produkte)
- Synonyme
- MAGP Protein, MAGP-1 Protein, MAGP1 Protein, AI893631 Protein, Magp Protein, Magp1 Protein, microfibril associated protein 2 Protein, microfibrillar-associated protein 2 Protein, MFAP2 Protein, Mfap2 Protein
- Hintergrund
- Microfibrillar-associated protein 2, also known as MFAP2, is an O-glycosylated protein secreted to the extracellular space and the extracellular matrix. MFAP2 associates with biglycan and elastin in a ternary complex. It is shown to play a significant role in the support and distensibility of the juxtacanalicular region of these collector channels. It is also reported to inhibit LTB-1 binding to fibrillin-1, stimulate the phosphorylation of Smad2, and thereby mediate the subsequent extracellular deposition of latent TGFbeta. Recombinant human MFAP2, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 21.5 kDa (190aa)
- NCBI Accession
- NP_002394
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