RAP2B Protein (His tag)

Produktnummer ABIN1098540

Produktdetails

Target: RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RAP2B Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Ras-related protein Rap-2b, RAP2B, member of RAS oncogene family

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))

Andere Bezeichnung: RAP2B (RAP2B Produkte)

Synonyme: Rap2b Protein, wu:fi34c06 Protein, zgc:55550 Protein, RAP2B Protein, LOC100223676 Protein, 4021402C18Rik Protein, AA408554 Protein, RAP2B, member of RAS oncogene family S homeolog Protein, RAP2B, member of RAS oncogene family Protein, RAS-like, family 10, member A Protein, GTP-binding protein Rhes pseudogene Protein, rap2b.S Protein, rap2b Protein, RASL10A Protein, RAP2B Protein, LOC100223676 Protein, Rap2b Protein

Hintergrund: Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 22.9kDa (206aa) confirmed by MALDI-TOF

NCBI Accession: NP_002877