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ARFIP2 Protein (His tag)

ARFIP2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN1098383
  • Target Alle ARFIP2 Proteine anzeigen
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses ARFIP2 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Aufreinigung
    purified by chromatography
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ARFIP2 Protein
  • Kommentare

    Synonyms: Arfaptin 2, POR1

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 40% glycerol,1 MM DTT
    Lagerung
    4 °C
    Informationen zur Lagerung
    Avoid repeated freezing and thawing cycles.
  • Target
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Andere Bezeichnung
    ARFIP2 (ARFIP2 Produkte)
    Synonyme
    POR1 Protein, 2310002N04Rik Protein, POR Protein, Por1 Protein, ARFIP2 Protein, im:7136059 Protein, zgc:112066 Protein, ADP ribosylation factor interacting protein 2 Protein, ADP-ribosylation factor interacting protein 2 Protein, ADP-ribosylation factor interacting protein 2b Protein, ARFIP2 Protein, Arfip2 Protein, arfip2b Protein
    Hintergrund
    Arfaptin 2, also known as ARFIP2, is a Rac1 binding protein necessary for Rac-mediated actin polymerization and the subsequent formation of membrane ruffles and lamellipodia. ARFIP2 has also been shown to interact with the ADP ribosylation factor ARF6, a GTPase that associates with the plasma membrane and intracellular endosome vesicles, in a GTP dependent manner. Arfaptin 2 also regulates the aggregation of mutant Huntingtin protein by possibly impairing proteasome function. Expression of ARFIP2 was shown to be increased at sites of neurodegeneration. Recombinant human ARFIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molekulargewicht
    40.2 kDa (364aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_036534
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