NPM1 Protein (His tag)

Produktnummer ABIN1098300

Produktdetails

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NPM1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Nucleophosmin, B23, NPM

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.15 M NaCl,1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Andere Bezeichnung: NPM1 (NPM1 Produkte)

Synonyme: B23 Protein, NPM Protein, NO38 Protein, Npm Protein, B23NP Protein, npm4 Protein, npm Protein, CG7917 Protein, CRP1 Protein, Crp1 Protein, Dmel\\CG7917 Protein, dNLP Protein, dNLP-S Protein, p22 Protein, npm1 Protein, sb:cb487 Protein, nucleophosmin 1 Protein, nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog Protein, nucleophosmin 1b Protein, Nucleophosmin Protein, nucleophosmin Protein, nucleophosmin (nucleolar phosphoprotein B23, numatrin) Protein, Nucleoplasmin Protein, nucleophosmin 1a Protein, NPM1 Protein, Npm1 Protein, npm1.L Protein, npm1b Protein, npm Protein, Nlp Protein, npm1a Protein

Hintergrund: NPM1 is a phosphoprotein which moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. Recombinant human NPM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 34.7kDa (314aa), confirmed by MALDI-TOF

NCBI Accession: NP_002511

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly