RGS1 Protein (His tag)
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- Target Alle RGS1 Proteine anzeigen
- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RGS1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Aufreinigung
- purified by chromatography
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RGS1 Protein
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Regulator of G-Protein Signaling 1 (RGS1) (AA 1-209) protein (His tag)
RGS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Regulator of G-Protein Signaling 1 (RGS1) (AA 1-196) protein (GST tag)RGS1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Regulator of G-Protein Signaling 1 (RGS1) (AA 1-209) protein (Strep Tag)Crystallography grade RGS1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Kommentare
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Synonyms: Regulator of G-protein signaling 1, 1R20, BL34, IER1, IR20
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
- Andere Bezeichnung
- RGS1 (RGS1 Produkte)
- Synonyme
- 1R20 Protein, BL34 Protein, IER1 Protein, IR20 Protein, RGS1 Protein, 1r20 Protein, bl34 Protein, ier1 Protein, ir20 Protein, regulator of G protein signaling 1 Protein, regulator of G-protein signaling 1 Protein, regulator of G-protein signaling 1 S homeolog Protein, Regulator of G-protein signaling 1 Protein, RGS1 Protein, Rgs1 Protein, rgs1.S Protein, rgs1 Protein
- Hintergrund
- RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Recombinant human RGS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 26 kDa (233aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_002913
- Pathways
- MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events
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