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PLXDC1 Protein (AA 19-426) (His tag)

PLXDC1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1097619
  • Target Alle PLXDC1 Proteine anzeigen
    PLXDC1 (Plexin Domain Containing 1 (PLXDC1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 19-426
    Spezies
    • 6
    • 3
    Human
    Quelle
    • 4
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses PLXDC1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Plexin Domain-Containing Protein 1/PLXDC1 (C-6His)
    Sequenz
    LSPQPGAGHD EGPGSGWAAK GTVRGWNRRA RESPGHVSEP DRTQLSQDLG GGTLAMDTLP DNRTRVVEDN HSYYVSRLYG PSEPHSRELW VDVAEANRSQ VKIHTILSNT HRQASRVVLS FDFPFYGHPL RQITMATGGF IFMGDVIHRM LTATQYVAPL MANFNPGYSD NSTVVYFDNG TVFVVQWDHV YLQGWEDKGS FTFQAALHHD GRIVFAYKEI PMSVPEISSS QHPVKTGLSD AFMILNPSPD VPESRRRSIF EYHRIELDPS KVTSMSAVEF TPLPTCLQHR SCDACMSSDL TFNCSWCHVL QRCSSGFDRY RQEWMDYGCA QEAEGRMCED FQDEDHDSAS PDTSFSPYDG DLTTTSSSLF IDSLTTEDDT KLNPYAGGDG LQNNLSPKTK GTPVHLGTVD HHHHHH
    Produktmerkmale
    Recombinant Human Plexin Domain-Containing Protein 1/PLXDC1 produced by transfected human cells is a secreted protein with sequence (Leu19 Thr426) of human PLXDC1/TEM7 fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PLXDC1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    PLXDC1 (Plexin Domain Containing 1 (PLXDC1))
    Andere Bezeichnung
    tem7 (PLXDC1 Produkte)
    Synonyme
    PLXDC1 Protein, TEM3 Protein, TEM7 Protein, 2410003I07Rik Protein, AI848450 Protein, Tem7 Protein, Arl12 Protein, plexin domain containing 1 Protein, PLXDC1 Protein, Plxdc1 Protein
    Sub Type
    Fusionprotein
    Hintergrund
    Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).
    Alternative Names: Plexin Domain-Containing Protein 1, Tumor Endothelial Marker 3, Tumor Endothelial Marker 7, PLXDC1, TEM3, TEM7
    Molekulargewicht
    46.53 kDa
    UniProt
    Q8IUK5
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