ST6GAL1 Protein (AA 27-406) (His tag)

Produktnummer ABIN1097583

Produktdetails

Target: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-406

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses ST6GAL1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human β-Galactoside α-2,6-Sialyltransferase 1/ST6GAL1 (C-6His)

Sequenz: KEKKKGSYYD SFKLQTKEFQ VLKSLGKLAM GSDSQSVSSS STQDPHRGRQ TLGSLRGLAK AKPEASFQVW NKDSSSKNLI PRLQKIWKNY LSMNKYKVSY KGPGPGIKFS AEALRCHLRD HVNVSMVEVT DFPFNTSEWE GYLPKESIRT KAGPWGRCAV VSSAGSLKSS QLGREIDDHD AVLRFNGAPT ANFQQDVGTK TTIRLMNSQL VTTEKRFLKD SLYNEGILIV WDPSVYHSDI PKWYQNPDYN FFNNYKTYRK LHPNQPFYIL KPQMPWELWD ILQEISPEEI QPNPPSSGML GIIIMMTLCD QVDIYEFLPS KRKTDVCYYY QKFFDSACTM GAYHPLLYEK NLVKHLNQGT DEDIYLLGKA TLPGFRTIHC VDHHHHHH

Produktmerkmale: Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1/ST6GAL1 produced by transfected human cells is a secreted protein with sequence (Lys27-Cys406) of Human ST6GAL1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Andere Bezeichnung: st6gal1 (ST6GAL1 Produkte)

Synonyme: SIAT1 Protein, ST6GalI Protein, ST6N Protein, Siat1 Protein, siat1 Protein, zgc:136454 Protein, ST6GAL1 Protein, AW742324 Protein, St6Gal-I Protein, St6gal Protein, St6galI Protein, ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Protein, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 Protein, beta galactoside alpha 2,6 sialyltransferase 1 Protein, ST6GAL1 Protein, St6gal1 Protein, st6gal1 Protein

Sub Type: Fusionprotein

Hintergrund: The ST6GAL1 gene encodes beta-Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galbeta1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
Alternative Names: Beta-Galactoside Alpha-2,6-Sialyltransferase 1, Alpha 2,6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1

Molekulargewicht: 44.6 kDa

UniProt: P15907