NAPA Protein (full length) (His tag)

Produktnummer ABIN1097553

Produktdetails

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Protein-Typ: Recombinant

Proteineigenschaft: full length

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NAPA Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human α-Soluble NSF Attachment Protein/SNAP-α/NAPA (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MDNSGKEAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN MFKMAKNWSA AGNAFCQAAQ LHLQLQSKHD AATCFVDAGN AFKKADPQEA INCLMRAIEI YTDMGRFTIA AKHHISIAEI YETELVDIEK AIAHYEQSAD YYKGEESNSS ANKCLLKVAG YAALLEQYQK AIDIYEQVGT NAMDSPLLKY SAKDYFFKAA LCHFCIDMLN AKLAVQKYEE LFPAFSDSRE CKLMKKLLEA HEEQNVDSYT ESVKEYDSIS RLDQWLTTML LRIKKTIQGD EEDLR

Produktmerkmale: Recombinant Human alpha-Soluble NSF Attachment Protein/SNAP-alpha produced by E.coli expression system.Target protein is expressed with sequence (Met1-Arg295) of Human SNAPalpha (Uniprot #P54920) fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Andere Bezeichnung: SNAPalpha (NAPA Produkte)

Synonyme: SNAPA Protein, wu:fa26c04 Protein, zgc:63906 Protein, napb Protein, 1500039N14Rik Protein, AW209189 Protein, RA81 Protein, SNARE Protein, a-SNAP Protein, hyh Protein, alpha-SNAP Protein, Alpha-SNAP Protein, NSF attachment protein alpha Protein, N-ethylmaleimide-sensitive factor attachment protein, alpha b Protein, NSF attachment protein alpha L homeolog Protein, N-ethylmaleimide-sensitive factor attachment protein, alpha Protein, N-ethylmaleimide sensitive fusion protein attachment protein alpha Protein, soluble NSF attachment protein Protein, NAPA Protein, napab Protein, napa.L Protein, napa Protein, EHI_000300 Protein, Napa Protein, LOC102577508 Protein

Sub Type: Fusionprotein

Hintergrund: Alpha-Soluble NSF Attachment Protein (SNAP-alpha) is a member of the SNAP (Soluble NSF Attachment Protein) family. SNAP-alpha interacts with PRKCABP and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. SNAP-alpha is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. SNAP-alpha is in charge of the binding of NSF and therefore the formation of a 20S fusion particle.
Alternative Names: Alpha-Soluble NSF Attachment Protein, SNAP-Alpha, N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha, NAPA, SNAPA

Molekulargewicht: 35.4 kDa

UniProt: P54920

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization