PFDN2 Protein (AA 1-154) (His tag)

Produktnummer ABIN1097397

Produktdetails

Target: PFDN2 (Prefoldin Subunit 2 (PFDN2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-154

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PFDN2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Prefoldin Subunit 2/PFDN2 (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MAENSGRAGK SSGSGAGKGA VSAEQVIAGF NRLRQEQRGL ASKAAELEME LNEHSLVIDT LKEVDETRKC YRMVGGVLVE RTVKEVLPAL ENNKEQIQKI IETLTQQLQA KGKELNEFRE KHNIRLMGED EKPAAKENSE GAGAKASSAG VLVS

Produktmerkmale:

Recombinant Human Prefoldin Subunit 2/PFDN2 (N-6His)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM NaCl, 1 mM DTT, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PFDN2 (Prefoldin Subunit 2 (PFDN2))

Andere Bezeichnung: Prefoldin Subunit 2/PFDN2 (PFDN2 Produkte)

Synonyme: im:6895552 Protein, wu:fb79a01 Protein, zgc:136473 Protein, ESTM27 Protein, W48336 Protein, PFD2 Protein, prefoldin subunit 2 Protein, prefoldin 2 Protein, pfdn2 Protein, EHI_113900 Protein, AOR_1_1714154 Protein, Pfdn2 Protein, PFDN2 Protein

Hintergrund: Recombinant Human Prefoldin Subunit 2/PFDN2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser143) of Human PFDN2 fused with a His tag at the N-terminus.
Prefoldin Subunit 2 (PFDN2) belongs to the Prefoldin β subunit family. The PFDN2 protein is one of six subunits of Prefoldin that act as a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. PFDN2 binds specifically to Cytosolic Chaperonin (c-CPN) and transfers target proteins to it. PFDN2 also binds to a nascent polypeptide chain and promotes folding in settings where there are many competing pathways for non-native proteins.

Molekulargewicht: 18.8 kDa

UniProt: Q9UHV9

Pathways: Unfolded Protein Response