BCAS2 Protein (AA 2-225) (His tag,T7 tag)

Produktnummer ABIN1097391

Produktdetails

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-225

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BCAS2 Protein ist gelabelt mit His tag,T7 tag.

Verwendungszweck: Recombinant Human BCAS2/DAM1 (C-6His, N-T7 tag)

Sequenz: MASMTGGQQM GRGSMAGTGL VAGEVVVDAL PYFDQGYEAP GVREAAAALV EEETRRYRPT KNYLSYLTAP DYSAFETDIM RNEFERLAAR QPIELLSMKR YELPAPSSGQ KNDITAWQEC VNNSMAQLEH QAVRIENLEL MSQHGCNAWK VYNENLVHMI EHAQKELQKL RKHIQDLNWQ RKNMQLTAGS KLREMESNWV SLVSKNYEIE RTIVQLENEI YQIKQQHGEA NKENIRQDFL EHHHHHH

Produktmerkmale: Recombinant Human Breast Carcinoma-Amplified Sequence 2/BCAS2 is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Phe225) of Human BCAS2 fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, 2 mM DTT, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Andere Bezeichnung: Breast Carcinoma-Amplified Sequence 2/BCAS2 (BCAS2 Produkte)

Synonyme: DAM1 Protein, SPF27 Protein, Snt309 Protein, 6430539P16Rik Protein, AI132645 Protein, C76366 Protein, C80030 Protein, BCAS2 Protein, cb302 Protein, zgc:101730 Protein, BCAS2, pre-mRNA processing factor Protein, breast carcinoma amplified sequence 2 Protein, breast carcinoma amplified sequence 2 L homeolog Protein, BCAS2 Protein, Bcas2 Protein, bcas2 Protein, bcas2.L Protein, CpipJ_CPIJ003889 Protein

Sub Type: Fusionprotein

Hintergrund: Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
Alternative Names: Pre-mRNA-Splicing Factor SPF27, Breast Carcinoma-Amplified Sequence 2, DNA Amplified in Mammary Carcinoma 1 Protein, Spliceosome-Associated Protein SPF 27, BCAS2, DAM1

Molekulargewicht: 28.58 kDa

UniProt: O75934