Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G) (Catalytic Subunit), (AA 1-323) protein (His tag)

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Proteinname
  • AI385652
  • Fin13
  • PP2CG
  • PP2CGAMMA
  • PPP2CG
  • protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
  • protein phosphatase, Mg2+/Mn2+ dependent 1G
  • protein phosphatase, Mg2+/Mn2+ dependent, 1G
  • Ppm1g
  • PPM1G
Proteineigenschaft
Catalytic Subunit, AA 1-323
4
4
3
2
1
1
1
1
1
Spezies
Human
18
1
Quelle
Escherichia coli (E. coli)
11
2
2
2
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
Dieses PPM1G Protein ist gelabelt mit His tag.
Applikation
Functional Studies (Func)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Verwendungszweck Recombinant Human Protein Phosphatase 1C Catalytic Subunit/PPP1CC (N, C-6His)
Sequenz MGSSHHHHHH SSGLVPRGSH MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE KKKPNATRPV TPPRGMITKQ AKKLEHHHHH H
Produktmerkmale Recombinant Human Serine/Threonine-Protein Phosphatase PP1-gamma Catalytic Subunit/PPP1CC is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Lys323) of Human PPP1CC fused with a 6His tag at both the N-terminus and C-terminus.
Reinheit > 95 % as determined by reducing SDS-PAGE.
Sterilität 0.2 μm filtered
Endotoxin-Niveau Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Sub Type Fusionprotein
Hintergrund Serine/Threonine-Protein Phosphatase PP1-Ypsilon Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.
Alternative Names: Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit, PP-1G, Protein Phosphatase 1C Catalytic Subunit, PPP1CC
Molekulargewicht 40.2 kDa
UniProt P36873
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Rekonstitution It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 1 mM DTT, pH 8.0 .
Konservierungs-mittel Dithiothreitol (DTT)
Vorsichtsmaßnahmen This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Lagerung -80 °C
Informationen zur Lagerung Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Haltbarkeit 6 months
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