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RTN4R Protein (AA 27-447) (His tag)

RTN4R Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1097242
  • Target Alle RTN4R Proteine anzeigen
    RTN4R (Reticulon 4 Receptor (RTN4R))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 27-447
    Spezies
    • 5
    • 4
    • 1
    • 1
    Human
    Quelle
    • 3
    • 3
    • 2
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses RTN4R Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Nogo-66 Receptor/Reticulon 4 Receptor/NgR/RTN4R (C-6His)
    Sequenz
    CPGACVCYNE PKVTTSCPQQ GLQAVPVGIP AASQRIFLHG NRISHVPAAS FRACRNLTIL WLHSNVLARI DAAAFTGLAL LEQLDLSDNA QLRSVDPATF HGLGRLHTLH LDRCGLQELG PGLFRGLAAL QYLYLQDNAL QALPDDTFRD LGNLTHLFLH GNRISSVPER AFRGLHSLDR LLLHQNRVAH VHPHAFRDLG RLMTLYLFAN NLSALPTEAL APLRALQYLR LNDNPWVCDC RARPLWAWLQ KFRGSSSEVP CSLPQRLAGR DLKRLAANDL QGCAVATGPY HPIWTGRATD EEPLGLPKCC QPDAADKASV LEPGRPASAG NALKGRVPPG DSPPGNGSGP RHINDSPFGT LPGSAEPPLT AVRPEGSEPP GFPTSGPRRR PGCSRKNRTR SHCRLGQAGS GGGGTGDSEG SVDHHHHHH
    Produktmerkmale
    Recombinant Human Nogo Receptor/NOGOR is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Cys27-Ser447) of Human NOGOR fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product RTN4R Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    RTN4R (Reticulon 4 Receptor (RTN4R))
    Andere Bezeichnung
    ngr (RTN4R Produkte)
    Synonyme
    NgR Protein, NGR Protein, NOGOR Protein, NgR1 Protein, Nogor Protein, reticulon 4 receptor Protein, rtn4r Protein, RTN4R Protein, Rtn4r Protein
    Sub Type
    Fusionprotein
    Hintergrund
    Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
    Alternative Names: Reticulon-4 Receptor, Nogo Receptor, NgR, Nogo-66 Receptor, RTN4R, NOGOR
    Molekulargewicht
    46.32 kDa
    UniProt
    Q9BZR6
    Pathways
    Neurotrophin Signalübertragung
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