MBIP Protein (AA 1-344) (His tag)

Produktnummer ABIN1097134

Produktdetails

Target: MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-344

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MBIP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIPP (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MAAATEHNRP SSGDRNLERR CSPNLSREVL YEIFRSLHTL VGQLDLRDDV VKITIDWNKL QSLSAFQPAL LFSALEQHIL YLQPFLAKLQ SPIKEENTTA VEEIGRTEMG NKNEVNDKFS IGDLQEEEKH KESDLRDVKK TQIHFDPEVV QIKAGKAEID RRISAFIERK QAEINENNVR EFCNVIDCNQ ENSCARTDAI FTPYPGFKSH VKVSRVVYTY GPQTRPEGIP GSGHKPNSML RDCGNQAVEE RLQNIEAHLR LQTGGPVPRD IYQRIKKLED KILELEGISP EYFQSVSFSG KRRKVQPPQQ NYSLAELDEK ISALKQALLR KSREAESMAT HHLPLEHHHH HH

Produktmerkmale: Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIP is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Pro344) of Human MBIP fused with a His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))

Andere Bezeichnung: MBIP (MBIP Produkte)

Synonyme: 4933408E06Rik Protein, MAP3K12 binding inhibitory protein 1 Protein, Mbip Protein, mbip Protein, MBIP Protein

Sub Type: Fusionprotein

Hintergrund: MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It’s function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.
Alternative Names: MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP

Molekulargewicht: 42.51 kDa

UniProt: Q9NS73