LAIR2 Protein (AA 22-152) (His tag)

Produktnummer ABIN1097053

Produktdetails

Target: LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-152

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses LAIR2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human LAIR-2/CD306 (C-6His)

Sequenz: QEGALPRPSI SAEPGTVISP GSHVTFMCRG PVGVQTFRLE REDRAKYKDS YNVFRLGPSE SEARFHIDSV SEGNAGLYRC LYYKPPGWSE HSDFLELLVK ESSGGPDSPD TEPGSSAGTV PGTEASGFDA PVDHHHHHH

Produktmerkmale: Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2/LAIR2 produced by transfected human cells is a secreted protein with sequence (Gln22-Pro152) of Human LAIR2 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))

Andere Bezeichnung: lair2 (LAIR2 Produkte)

Synonyme: CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein

Sub Type: Fusionprotein

Hintergrund: Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.
Alternative Names: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2

Molekulargewicht: 15.1 kDa

UniProt: Q6ISS4