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FETUB Protein (AA 16-382) (His tag)

FETUB Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1096645
  • Target Alle FETUB Proteine anzeigen
    FETUB (Fetuin B (FETUB))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 16-382
    Spezies
    • 5
    • 4
    • 4
    • 3
    Human
    Quelle
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses FETUB Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Fetuin-B/FETUB (C-6His)
    Sequenz
    CGAMSPPQLA LNPSALLSRG CNDSDVLAVA GFALRDINKD RKDGYVLRLN RVNDAQEYRR GGLGSLFYLT LDVLETDCHV LRKKAWQDCG MRIFFESVYG QCKAIFYMNN PSRVLYLAAY NCTLRPVSKK KIYMTCPDCP SSIPTDSSNH QVLEAATESL AKYNNENTSK QYSLFKVTRA SSQWVVGPSY FVEYLIKESP CTKSQASSCS LQSSDSVPVG LCKGSLTRTH WEKFVSVTCD FFESQAPATG SENSAVNQKP TNLPKVEESQ QKNTPPTDSP SKAGPRGSVQ YLPDLDDKNS QEKGPQEAFP VHLDLTTNPQ GETLDISFLF LEPMEEKLVV LPFPKEKART AECPGPAQNA SPLVLPPVDH HHHHH
    Produktmerkmale
    Recombinant Human Fetuin-B is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Cys16-Pro382) of Human FETUB fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product FETUB Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    FETUB (Fetuin B (FETUB))
    Andere Bezeichnung
    fetuin-b (FETUB Produkte)
    Synonyme
    16G2 Protein, Gugu Protein, IRL685 Protein, Fet Protein, Pp63 Protein, gugu Protein, fetuin-b Protein, FETUB Protein, 16g2 Protein, irl685 Protein, im:6910148 Protein, 2310011O17Rik Protein, AI255764 Protein, D17980 Protein, fetuin B Protein, fetuin B L homeolog Protein, fetuin beta Protein, FETUB Protein, Fetub Protein, fetub.L Protein, fetub Protein
    Sub Type
    Fusionprotein
    Hintergrund
    Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20% amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.
    Alternative Names: Fetuin-B, 16G2, Fetuin-Like Protein IRL685, Gugu, FETUB
    Molekulargewicht
    41.53 kDa
    UniProt
    Q9UGM5
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