CCL3L1 Protein (AA 24-93) (His tag)

Produktnummer ABIN1096281

Produktdetails

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 24-93

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CCL3L1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human C-C Motif Chemokine 3-Like 1/CCL3L1 (C-6His)

Sequenz: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLEPSA VDHHHHHH

Produktmerkmale: Recombinant Human C-C Motif Chemokine 3-Like 1/CCL3L1 produced by transfected human cells is a secreted protein with sequence (Ala24-Ala93) of human CCL3L1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Andere Bezeichnung: ccl3l1 (CCL3L1 Produkte)

Synonyme: 464.2 Protein, D17S1718 Protein, G0S19-2 Protein, LD78 Protein, LD78BETA Protein, MIP1AP Protein, SCYA3L Protein, SCYA3L1 Protein, C-C motif chemokine ligand 3 like 1 Protein, chemokine (C-C motif) ligand 3-like 1 Protein, CCL3L1 Protein

Sub Type: Fusionprotein

Hintergrund: C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. The copy number of this gene varies among individuals: most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene. This record represents the more centromeric full-length gene.
Alternative Names: C-C Motif Chemokine 3-Like 1, G0/G1 Switch Regulatory Protein 19-2, LD78-Beta(1-70), PAT 464.2, Small-Inducible Cytokine A3-Like 1, Tonsillar Lymphocyte LD78 Beta Protein, CCL3L1, D17S1718, G0S19-2, SCYA3L1, CCL3L3

Molekulargewicht: 8.82 kDa

UniProt: P16619

Pathways: Cellular Response to Molecule of Bacterial Origin