Cathepsin E Protein (CTSE) (AA 20-396) (His tag)

Produktnummer ABIN1096239

Produktdetails

Target: Cathepsin E (CTSE)

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-396

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Cathepsin E Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cathepsin E/CTSE (C-6His)

Sequenz: SLHRVPLRRH PSLKKKLRAR SQLSEFWKSH NLDMIQFTES CSMDQSAKEP LINYLDMEYF GTISIGSPPQ NFTVIFDTGS SNLWVPSVYC TSPACKTHSR FQPSQSSTYS QPGQSFSIQY GTGSLSGIIG ADQVSVEGLT VVGQQFGESV TEPGQTFVDA EFDGILGLGY PSLAVGGVTP VFDNMMAQNL VDLPMFSVYM SSNPEGGAGS ELIFGGYDHS HFSGSLNWVP VTKQAYWQIA LDNIQVGGTV MFCSEGCQAI VDTGTSLITG PSDKIKQLQN AIGAAPVDGE YAVECANLNV MPDVTFTING VPYTLSPTAY TLLDFVDGMQ FCSSGFQGLD IHPPAGPLWI LGDVFIRQFY SVFDRGNNRV GLAPAVPVDH HHHHH

Produktmerkmale:

Recombinant Human Cathepsin E/CTSE (C-6His)

Specific Activity is greater than 350pmol/min/ugMeasured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Cathepsin E (CTSE)

Andere Bezeichnung: Cathepsin E (CTSE Produkte)

Synonyme: CATE Protein, A430072O03Rik Protein, C920004C08Rik Protein, CE Protein, CatE Protein, CEA Protein, CEB Protein, Ctsea Protein, CTSE Protein, ce1 Protein, ce2 Protein, cate Protein, CE1 Protein, ce1-A Protein, ctse Protein, CE2 Protein, ce2-A Protein, cathepsin E Protein, cathepsin E L homeolog Protein, cathepsin E S homeolog Protein, CTSE Protein, Ctse Protein, TP03_0056 Protein, Smp_184930 Protein, ctse Protein, ctse.L Protein, ctse.S Protein

Hintergrund: Recombinant Human Cathepsin E is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser20-Pro396) of Human CTSE fused with a polyhistidine tag at the C-terminus.
Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. It is expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. CTSE is an intracellular proteinase that have a role in immune function, activation-induced lymphocyte depletion in the thymus, neuronal degeneration and glial cell activation in the brain. Futhermore, it probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation.

Molekulargewicht: 41.78 kDa

UniProt: P14091