BAG2 Protein (AA 1-211) (His tag)

Produktnummer ABIN1096077

Produktdetails

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-211

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BAG2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Bcl-2-Associated Athanogene 1/BAG2 (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET IRNPQQQESL KHATRIIDEV VNKFLDDLGN AKSHLMSLYS ACSSEVPHGP VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEHSKGAGSK TLQQNAESRF N

Produktmerkmale: Recombinant Human BAG Family Molecular Chaperone Regulator 2/BAG2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn211) of Human BAG2 fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BAG2 (BAG2 Produkte)

Synonyme: bag2 Protein, MGC89300 Protein, BAG2 Protein, ATBAG2 Protein, BCL-2-associated athanogene 2 Protein, MTG10.13 Protein, MTG10_13 Protein, BAG-2 Protein, dJ417I1.2 Protein, zgc:64195 Protein, 2610042A13Rik Protein, BC016230 Protein, BCL2 associated athanogene 2 Protein, BCL-2-associated athanogene 2 Protein, BCL2-associated athanogene 2 Protein, Bcl2-associated athanogene 2 Protein, bag2 Protein, BAG2 Protein, Bag2 Protein

Sub Type: Fusionprotein

Hintergrund: BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Alternative Names: BAG Family Molecular Chaperone Regulator 2, BAG-2, Bcl-2-Associated Athanogene 2, BAG2

Molekulargewicht: 25.9 kDa

UniProt: O95816