COL4a2 Protein (AA 1493-1712, partial) (His tag)
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- Target Alle COL4a2 (COL4A2) Proteine anzeigen
- COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1493-1712, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses COL4a2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS), ELISA
- Sequenz
- VKHSQTDQEP MCPVGMNKLW SGYSLLYFEG QEKAHNQDLG LAGSCLARFS TMPFLYCNPG DVCYYASRND KSYWLSTTAP LPMMPVAEDE IKPYISRCSV CEAPAIAIAV HSQDVSIPHC PAGWRSLWIG YSFLMHTAAG DEGGGQSLVS PGSCLEDFRA TPFIECNGGR GTCHYYANKY SFWLTTIPEQ SFQGSPSADT LKAGLIRTHI SRCQVCMKNL
- Produktmerkmale
- Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Ref.13 Ref.17 Ref.18 Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. Ref.13 Ref.17 Ref.18
- Reinheit
- 90 %
- Top Product
- Discover our top product COL4A2 Protein
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Collagen, Type IV, alpha 2 (COL4A2) (AA 1481-1707) protein (His-IF2DI Tag)
COL4A2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Collagen, Type IV, alpha 2 (COL4A2) (AA 1486-1712) protein (His tag)Crystallography grade COL4A2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type IV, alpha 2 (COL4A2) (AA 1481-1707) protein (His tag)Crystallography grade COL4A2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type IV, alpha 2 (COL4A2) (AA 184-1712) protein (His tag)Crystallography grade COL4A2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type IV, alpha 2 (COL4A2) (AA 184-1707) protein (His tag)Crystallography grade COL4A2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Kommentare
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 6M guanidine hydrochloride, 20mM Tris
- Lagerung
- -20 °C
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- Target
- COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
- Andere Bezeichnung
- Collagen alpha-2(IV) chain (COL4A2 Produkte)
- Synonyme
- col4a2-a Protein, zCanstatin Protein, ICH Protein, POREN2 Protein, Col4a-2 Protein, collagen, type IV, alpha 2 L homeolog Protein, collagen type IV alpha 2 chain Protein, collagen, type IV, alpha 2 Protein, col4a2.L Protein, COL4A2 Protein, col4a2 Protein, Col4a2 Protein
- Molekulargewicht
- 28.3 kD
- UniProt
- P08572
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