COL4A1 Protein (AA 30-167, partial) (GST tag)

Produktnummer ABIN1046837

Produktdetails

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-167, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses COL4A1 Protein ist gelabelt mit GST tag.

Applikation: SDS-PAGE (SDS), ELISA

Sequenz: GCAGSGCGKC DCHGVKGQKG ERGLPGLQGV IGFPGMQGPE GPQGPPGQKG DTGEPGLPGT KGTRGPPGAS GYPGNPGLPG IPGQDGPPGP PGIPGCNGTK GERGPLGPPG LPGFAGNPGP PGLPGMKGDP GEILGHVP

Produktmerkmale: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Ref.12 Ref.17 Ref.18 Ref.19 Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS buffer, 20mM GSH

Lagerung: -20 °C

Antigendetails

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Andere Bezeichnung: Collagen alpha-1(IV) chain (COL4A1 Produkte)

Synonyme: col4a1 Protein, wu:fc02g11 Protein, HANAC Protein, ICH Protein, POREN1 Protein, arresten Protein, Bru Protein, Col4a-1 Protein, Del(8)44H Protein, Raw Protein, Svc Protein, collagen, type IV, alpha 5 (Alport syndrome) Protein, collagen type IV alpha 1 chain Protein, collagen, type IV, alpha 1 Protein, col4a5 Protein, COL4A1 Protein, Col4a1 Protein

Molekulargewicht: 40.3 kD

UniProt: P02462

Pathways: Skeletal Muscle Fiber Development, Growth Factor Binding