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CBR1 Protein (AA 2-277, full length) (GST tag)

CBR1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Produktnummer ABIN1046764
  • Target Alle CBR1 Proteine anzeigen
    CBR1 (Carbonyl Reductase 1 (CBR1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 2-277, full length
    Spezies
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 7
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CBR1 Protein ist gelabelt mit GST tag.
    Applikation
    SDS-PAGE (SDS), ELISA
    Sequenz
    SSGIHVALVT GGNKGIGLAI VRDLCRLFSG DVVLTARDVT RGQAAVQQLQ AEGLSPRFHQ LDIDDLQSIR ALRDFLRKEY GGLDVLVNNA GIAFKVADPT PFHIQAEVTM KTNFFGTRDV CTELLPLIKP QGRVVNVSSI MSVRALKSCS PELQQKFRSE TITEEELVGL MNKFVEDTKK GVHQKEGWPS SAYGVTKIGV TVLSRIHARK LSEQRKGDKI LLNACCPGWV RTDMAGPKAT KSPEEGAETP VYLALLPPDA EGPHGQFVSE KRVEQW
    Produktmerkmale
    NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
    Reinheit
    90 %
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  • Kommentare

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS buffer, 20mM GSH
    Lagerung
    -20 °C
  • Target
    CBR1 (Carbonyl Reductase 1 (CBR1))
    Andere Bezeichnung
    Carbonyl reductase [NADPH] 1 (CBR1 Produkte)
    Synonyme
    LOC100222525 Protein, MGC131152 Protein, CBR Protein, SDR21C1 Protein, hCBR1 Protein, 9-KPR Protein, AW261796 Protein, CR Protein, Cbr Protein, carbonyl reductase 1 Protein, carbonyl reductase [NADPH] 1 Protein, carbonyl reductase 1 S homeolog Protein, carbonyl reductase Protein, cbr1 Protein, CBR1 Protein, LOC100222525 Protein, cbr1.S Protein, Smp_033530.3 Protein, LOC610164 Protein, Cbr1 Protein
    Hintergrund
    Synonyms: 15-hydroxyprostaglandin dehydrogenase [NADP+] NADPH-dependent carbonyl reductase 1 Prostaglandin 9-ketoreductase Prostaglandin-E(2) 9-reductase
    Molekulargewicht
    57.6 kD
    UniProt
    P16152
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