CBR1 Protein (AA 2-277, full length) (GST tag)
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- Target Alle CBR1 Proteine anzeigen
- CBR1 (Carbonyl Reductase 1 (CBR1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 2-277, full length
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses CBR1 Protein ist gelabelt mit GST tag.
- Applikation
- SDS-PAGE (SDS), ELISA
- Sequenz
- SSGIHVALVT GGNKGIGLAI VRDLCRLFSG DVVLTARDVT RGQAAVQQLQ AEGLSPRFHQ LDIDDLQSIR ALRDFLRKEY GGLDVLVNNA GIAFKVADPT PFHIQAEVTM KTNFFGTRDV CTELLPLIKP QGRVVNVSSI MSVRALKSCS PELQQKFRSE TITEEELVGL MNKFVEDTKK GVHQKEGWPS SAYGVTKIGV TVLSRIHARK LSEQRKGDKI LLNACCPGWV RTDMAGPKAT KSPEEGAETP VYLALLPPDA EGPHGQFVSE KRVEQW
- Produktmerkmale
- NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
- Reinheit
- 90 %
- Top Product
- Discover our top product CBR1 Protein
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- Kommentare
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH
- Lagerung
- -20 °C
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- Target
- CBR1 (Carbonyl Reductase 1 (CBR1))
- Andere Bezeichnung
- Carbonyl reductase [NADPH] 1 (CBR1 Produkte)
- Synonyme
- LOC100222525 Protein, MGC131152 Protein, CBR Protein, SDR21C1 Protein, hCBR1 Protein, 9-KPR Protein, AW261796 Protein, CR Protein, Cbr Protein, carbonyl reductase 1 Protein, carbonyl reductase [NADPH] 1 Protein, carbonyl reductase 1 S homeolog Protein, carbonyl reductase Protein, cbr1 Protein, CBR1 Protein, LOC100222525 Protein, cbr1.S Protein, Smp_033530.3 Protein, LOC610164 Protein, Cbr1 Protein
- Hintergrund
- Synonyms: 15-hydroxyprostaglandin dehydrogenase [NADP+] NADPH-dependent carbonyl reductase 1 Prostaglandin 9-ketoreductase Prostaglandin-E(2) 9-reductase
- Molekulargewicht
- 57.6 kD
- UniProt
- P16152
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