CXCL10 Protein (AA 22-98, full length) (His tag)

Produktnummer ABIN1046707

Produktdetails

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-98, full length

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CXCL10 Protein ist gelabelt mit His tag.

Applikation: ELISA

Sequenz: VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Referenzen

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Hensbergen, van der Raaij-Helmer, Dijkman, van der Schors, Werner-Felmayer, Boorsma, Scheper, Willemze, Tensen: "Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity." in: European journal of biochemistry / FEBS, Vol. 268, Issue 18, pp. 4992-9, (2001) (PubMed).

Tensen, Flier, Van Der Raaij-Helmer, Sampat-Sardjoepersad, Van Der Schors, Leurs, Scheper, Boorsma, Willemze: "Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)." in: The Journal of investigative dermatology, Vol. 112, Issue 5, pp. 716-22, (1999) (PubMed).

Proost, De Wolf-Peeters, Conings, Opdenakker, Billiau, Van Damme: "Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 3, pp. 1000-10, (1993) (PubMed).

Luster, Unkeless, Ravetch: "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins." in: Nature, Vol. 315, Issue 6021, pp. 672-6, (1985) (PubMed).

Antigendetails

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Andere Bezeichnung: C-X-C motif chemokine 10 protein (CXCL10 Produkte)

Synonyme: CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein

Hintergrund: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.

Molekulargewicht: 12.7 kD

UniProt: P02778