CCL24 Protein (AA 27-119, full length) (His tag)

Produktnummer ABIN1095507

Produktdetails

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-119, full length

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CCL24 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS), ELISA

Sequenz: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVAVK GPVQRYPGNQ TTC

Produktmerkmale: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 6M guanidine hydrochloride, 20mM Tris

Lagerung: -20 °C

Referenzen

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

White, Imburgia, Dul, Appelbaum, ODonnell, OShannessy, Brawner, Fornwald, Adamou, Elshourbagy, Kaiser, Foley, Schmidt, Johanson, Macphee, Moores, McNulty, Scott, Schleimer, Sarau: "Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils." in: Journal of leukocyte biology, Vol. 62, Issue 5, pp. 667-75, (1997) (PubMed).

Patel, Kreider, Li, Li, Leung, Salcedo, Nardelli, Pippalla, Gentz, Thotakura, Parmelee, Gentz, Garotta: "Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors." in: The Journal of experimental medicine, Vol. 185, Issue 7, pp. 1163-72, (1997) (PubMed).

Antigendetails

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Andere Bezeichnung: C-C motif chemokine 24 (CCL24 Produkte)

Synonyme: Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein

Hintergrund: Synonyms: CK-beta-6 Eosinophil chemotactic protein 2 Eotaxin-2 Myeloid progenitor inhibitory factor 2 Short name=MPIF-2 Small-inducible cytokine A24

Molekulargewicht: 14.6 kD

UniProt: O00175

Pathways: Regulation of Actin Filament Polymerization