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Alfa-1 Antitrypsin Protein

Spezies: Human Wirt: Rice (Oryza sativa) Recombinant > 95 % , SDS Page
Produktnummer ABIN1042573
  • Target
    Alfa-1 Antitrypsin
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 1
    Rice (Oryza sativa)
    Produktmerkmale
    Activity: 3-5mg OsrAATwill inhibit 1mg PPE with an activity of 10.8 units per mg protein
    Formulation: Lyophilized from a 200 myL sterile-filtered solution added Osr HSA for protection.
    Reinheit
    > 95 % , SDS Page
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS pH7.0
    Lagerung
    -20 °C
  • Zhang, Shi, Jiang, Stupak, Ou, Qiu, An, Li, Yang: "Expression and characterization of recombinant human alpha-antitrypsin in transgenic rice seed." in: Journal of biotechnology, Vol. 164, Issue 2, pp. 300-8, (2013) (PubMed).

  • Target
    Alfa-1 Antitrypsin
    Synonyme
    A1A Protein, A1AT Protein, AAT Protein, PI Protein, PI1 Protein, PRO2275 Protein, alpha1AT Protein, serpin family A member 1 Protein, SERPINA1 Protein
    Hintergrund
    OsrAAT is a Human Recombinant protein produced in Rice, which is a single, non-glycosylated polypeptidechain containing 384 amino acids and has a molecular mass of 43.1 kDa. OsrAAT is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. In its absence, neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children. The OsrAAT protein is purified by chromatographic techniques.
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